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Hostility toward women is a frequently examined risk factor for sexual or physical aggression against women, but it is also associated with other violent offenses. Thus, examining the risk factors for hostility toward women is of particular relevance for the prevention of violence against women. As a matter of fact, psychopathy-related aspects (e.g., antisociality, callousness, unemotional traits, narcissism) are associated with hostility toward women and sexual aggression. However, research indicate that other variables related to cognitive, emotional or individual characteristics also have an effect on hostility toward women. The aim of our study is to examine which factor can alter the relationship between antisocial characteristics and hostility toward women. We conducted a series of moderation analyses on a Canadian sample of sexual aggressors of women (n = 206) to examine which factor reduces or increases the risk of developing hostility toward women while already having antisocial traits. Implications for research and treatment of sexual aggressors will be discussed.