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This study uses a qualitative semi-structured interview study design with a sample of U.S. biopsychosocial, neurocriminology, and neurolaw/ethics professors, to explore the question of how neuroscience should be used in the courtroom and in criminal justice more generally, asking questions about the legal and ethical implications, as well its relevance in judgments of responsibility and punishment. Ultimately, this research expands existing literature to explore unstudied legal and ethical questions that may arise when neuroscience and mental health are involved in criminal justice processes, as well as provides crucial information that should assist in creating more effective and equitable policies and practices in the criminal justice system.