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Individuals released from incarceration face heightened risk of fatal drug overdose. Medication for Opioid Use Disorder (MOUD) during incarceration may reduce this risk, but post-release outcomes among individuals with MOUD access remain underexplored. The Orange County Florida jail has implemented a program to begin MOUD with individuals during their incarceration. To assess the impact of access to MOUD in the Orange County Jail on post-release fatal overdoses and measures of well-being, two primary datasets were used for analysis. The first included all unintentional overdose deaths in Orange County for 2024 and 2025, obtained from the Medical Examiner’s Office. The second consisted of data from the Jail’s Health Services division. Key measures included demographic variables (e.g., age, gender, race) and incarceration-specific factors (e.g., length of stay, completion of assessments, type of MOUD used, and related indicators) to help identify risk and protective factors associated with post-release outcomes. The results of this study help to identify those at most risk of negative outcomes post-incarceration and factors that contribute to long-term success and reduce recidivism.