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The UKRI funded Researcher Wellbeing Project addresses a gap in understanding the impact of potentially sensitive research on researchers across various disciplines. Focusing on the impacts on wellbeing, the study also aimed to understand the underlying factors increasing researchers' vulnerability to distress. Using a mixed-methods approach, 31 semi-structured interviews were conducted with academic staff working on sensitive research topics. The Secondary Trauma Stress (STS) Scale was also used to assess participants' symptom severity for descriptive statistics. Participants' experiences and impacts on their wellbeing were analysed using thematic analysis. Researchers reported a spectrum of psychological and physical symptoms aligned with ‘PTSD-like’ symptoms. Most common symptoms included trouble concentrating, negative emotions, and distressing thoughts. Just over a third reported gaps in memory, hyperarousal and avoidance. Beyond the STS symptoms, the study also demonstrated that researchers’ social relationships were impacted. Factors increasing vulnerability to distress included limited control over research topics, inadequate coping strategies, shared experiences with traumatised groups, and personal life challenges. The study underlines the need for institutional support systems, including training in coping strategies and guidelines for conducting sensitive research. It highlights the importance of a collaborative approach to address the wellbeing of researchers, moving beyond individual resilience to foster a supportive research environment. Specific implications include developing training programs, peer support groups, and regular wellbeing check-ins to mitigate risks associated with potentially traumatic research topics.