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Zika virus infection has been reported in Singapore since 2016, which is particularly vulnerable to pregnant women. Dealing with the issue of the Zika virus outbreak in Singapore, this study explores the use of different media for getting information about Zika virus among Singaporean women of childbearing age and its relationships with their risk perceptions and prevention behavior toward Zika virus. The preliminary data analysis from a national survey of 510 Singaporean women shows that exposure to Zika virus information on social networking sites is significantly related to risk perceptions, pregnancy concern, and prevention behavior. Further research has been designed to examine the relationship among Singaporean women’s motivations to use of social networking sites for Zika virus information, risk perceptions, and prevention behavior.