1-031 - Development of brain networks: Insights from resting-state functional connectivity studies of the amygdala and hippocampus

Session Type: Paper Symposium

Integrative Statement

Understanding development of brain networks is a primary goal within the field of developmental cognitive neuroscience (Johnson, 2010). The ability to identify large-scale, functionally-relevant brain networks independent of a task (i.e., rest-state functional connectivity networks) is a recent advance in cognitive neuroscience that offers significant insight into the study of brain organization. This technique is proving particularly useful in examining developmental change because the cognitive burden of performing a task while remaining motionless is eliminated and thus the technique can be used with very young children and across large developmental windows (Casey et al., 2005; Uddin et al., 2010). Despite substantial reorganization of functional connectivity across development, several large-scale network properties appear to be preserved across the lifespan, suggesting that functional brain networks, even in children, are organized in manners similar to other complex systems (Power et al., 2010). This symposium will focus on highlighting developmental changes in medial temporal lobe networks, identified by anatomical seeds in the amygdala and hippocampus. The presentations will discuss changes early in life (Blankenship et al.), specificity of these changes (Gabard-Durnam et al. & Chai et al.), and the relevance of these changes for behavior (Redcay et al.). Our hope is that the presentation and discussion of these findings will encourage the field to move beyond traditional questions of what brain regions are recruited during a specific task at various ages, to questions related to how brain networks change as a function of age and result in changes at the behavioral level.

Sub Unit

• Biological Processes

Chairs

• Lea Rose Dougherty, University of Maryland, College Park

• Tracy Riggins, University of Maryland

Individual Presentations

• Development of hippocampal resting-state networks during childhood - Presenting Author: Sarah Louise Blankenship, University of Maryland, College Park; Lea Rose Dougherty, University of Maryland, College Park; Elizabeth Redcay, University of Maryland, College Park; Tracy Riggins, University of Maryland

• Resting-state amygdala-cortical circuit development and associations with previous experiences - Presenting Author: Laurel J. Gabard-Durnam, Columbia University; Dylan G. Gee; Jessica Flannery, UCLA; Bonnie Goff, UCLA; Kathryn Humphreys, UCLA; Eva H Telzer, University of Illinois, Urbana-Champaign; Todd Hare, University of Zurich; Dominic Fareri, UCLA; Christina Caldera, UCLA; Daniel Lumian, University of California, Los Angeles; Nim Tottenham, Columbia Univ

• Development of amygdala and hippocampal resting-state functional connectivity between 8 to 24 years of age - Presenting Author: Xiaoqian Chai, MIT; noa ofen, Wayne State University; Rebecca Martin, Columbia University; Susan Whitfield-Gabrieli, MIT; John D Gabrieli, MIT

• Amygdala-prefrontal network development during early childhood - Presenting Author: Elizabeth Redcay, University of Maryland, College Park; Katherine Rice, University of Maryland, College Park; Sarah Louise Blankenship, University of Maryland, College Park; Tracy Riggins, University of Maryland