3-195 - Cognitive Control Networks in Context

Session Type: Paper Symposium

Integrative Statement

Developmental cognitive neuroimaging provides an unprecedented view of the mechanisms underlying cognitive maturation. In this symposium, we explore the neurobiological origins and protracted development of task control, which encompasses cognitive processes necessary for adapting to changing task demands in pursuit of a goal. The first paper investigates the stabilization of cognitive control networks in a large, age-sensitive sample. The findings suggest that variation in whole-brain patterns associated with task control decrease across age and predict decreased variation in task performance. The second paper evaluates the consistency of activity in control-related networks across three tasks in middle childhood, and finds that brain regions involved in task control are not uniformly engaged across control-demanding tasks as they are in adulthood. The third paper investigates the development of network connectivity and reasoning ability in a large longitudinal sample, finding that structural connectivity among fronto-parietal regions positively relates to reasoning ability and predicts gains in this ability across time. The final paper uses innovative multivariate analyses to identify large-scale brain networks that can reliably distinguish children and adolescents with and without Tourette syndrome. The analyses converge upon reliable differences between these groups, with the most profound differences emerging in control networks. Together, these papers refine our understanding of the maturation of task-control networks across typical and atypical populations. This symposium moves beyond previous work on control networks by exploring multivariate analysis and by focusing not only on mean values, but also on variability across and within individuals over time.

Sub Unit

• Biology and Neuroscience

Chair

• Jessica Church, The University of Texas at Austin

Individual Presentations

• Stabilization of cognitive brain states underlies working memory development - Presenting Author: Beatriz Luna, University of Pittsburgh; David Montez, University of Pittsburgh; Finnegan Calabro, Department of Psychiatry, University of Pittsburgh

• Task-control network activity over three control-demanding tasks in middle childhood - Presenting Author: Laura Engelhardt, University of Texas at Austin; K. Paige Harden, University of Texas at Austin; Elliot M Tucker-Drob, University of Texas at Austin; Jessica Church, The University of Texas at Austin

• Fronto-parietal structural connectivity, functional connectivity, and reasoning ability in a large-scale longitudinal study - Carter Wendelken, UC Berkeley; Presenting Author: Susan Whitfield-Gabrieli, MIT; Emilio Ferrer, UC Davis; Simona Ghetti, University of California-Davis; Stephen K Bailey, Vanderbilt University; Laurie Cutting, Vanderbilt University; Silvia Bunge, University of California Berkeley

• Multivariate methods reveal atypical large-scale brain networks in pediatric Tourette syndrome - Presenting Author: Deanna Greene, Washington University in St. Louis; Jessica Church, The University of Texas at Austin; Ashley Nielsen, Washington University in St. Louis; Nico Dosenbach, Washington University in St. Louis; Steven Petersen, Washington University in St. Louis; Kevin Black, Washington University in St. Louis; Bradley Schlaggar, Washington University in St. Louis