3-118 - Neurodevelopmental Consequences of Parenting and Family Adversity: Brain Imaging Findings from Three Cohort Studies

Session Type: Paper Symposium

Integrative Statement

This symposium brings together neuroimaging research from cohort studies across different countries with the purpose of understanding the effects of parenting and family factors on child neurodevelopment, in particular emotion regulation circuitry. The first paper presents findings from three MRI studies using longitudinal methods and repeated imaging to examine how family conflict, maternal depression, and observed mother-infant attachment relate to neural processing and risk taking. The second paper reports findings from the Adolescent Brain Cognitive Development (ABCD) study, which includes children across 21 sites in the United States, and examines associations between maternal and paternal monitoring and acceptance and resting state fMRI connectivity. The final paper discusses results from the Generation R longitudinal population-based cohort of families in The Netherlands and examines parental conflict prenatally and repeatedly across childhood and children’s structural brain development. The papers utilize different neuroimaging modalities: structural, resting state and task-based functional MRI. Importantly, across different modalities, offspring ages, and reports/methods of assessing family adversity (mother, father, youth reports, observation), results consistently point to parenting and family factors as significant influences on the regions of the brain involved in emotion regulation. The symposium will end with a discussion of how such studies inform our understanding of child development research and practice. The discussant is an expert in child development and resilience, and is the director of a center for integrative research on childhood adversity.

Sub Unit

• Biological Processes: Neuroscience and Genetics

Chair

• Amanda Morris, Oklahoma State University

Discussant

• Jennifer Hays-Grudo, Oklahoma State University

Individual Presentations

• Family Relationship Quality and Adolescent Neural Processing of Risk Taking - Presenting Author: Eva H. Telzer, University of North Carolina Chapel Hill; Non-Presenting Author: Ethan M. McCormick, University of North Carolina Chapel Hill; Non-Presenting Author: Nancy McElwain, University of Illinois at Urbana-Champaign; Non-Presenting Author: Yang Qu, Northwestern University

• Parenting and Functional Connectivity in the Emotion Regulation Circuity of Pre-adolescents: The ABCD Study - Non-Presenting Author: Amanda Morris, Oklahoma State University; Presenting Author: Hannah Kim, Harvard TH Chan School of Public Health; Non-Presenting Author: Kara L. Kerr, Oklahoma State University; Non-Presenting Author: Florence Breslin, Laureate Institute for Brain Research; Non-Presenting Author: Henning Tiemeier, Harvard TH Chan School of Public Health, Boston; Non-Presenting Author: Martin Paulus, Laureate Institute for Brain Research

• Parental Conflict from Pregnancy Onward and Preadolescent Brain Development: The Mediating Role of Child Problem Behavior - Presenting Author: Henning Tiemeier, Harvard TH Chan School of Public Health, Boston; Non-Presenting Author: Yllza Xerxa, 2Department of Child and Adolescent Psychiatry, Erasmus MC, Rotterdam, the Netherlands; Non-Presenting Author: Pauline Jansen, Erasmus MC-University Medical Center Rotterdam, The Netherlands; Non-Presenting Author: Ryan Muetzel, University Medical Center Rotterdam, the Netherlands; Non-Presenting Author: Tonya White, University Medical Center Rotterdam