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3-064 - The Effects of Environmental Toxicity on Neurodevelopmental Outcomes Across Infancy and Early Childhood

Sat, March 23, 9:45 to 11:15am, Baltimore Convention Center, Floor: Level 3, Room 322

Session Type: Paper Symposium

Integrative Statement

The adverse effects of exposure to environmental toxicants on children’s development is a significant public health concern. Research on the scope, severity and onset of such effects can inform early interventions to address exposure-related developmental delays. Toward this end, the overarching focus of this symposium is the empirical study of the effects of different types of environmental exposures on children’s performance on various measures of neurocognitive development at earliest ages possible. The papers in this session include data from three research centers within the Environmental influences on Child Health Outcomes program (ECHO), a large national study consisting of 85 cohorts across the United States. Paper 1 examines the effects of mothers’ prenatal exposure to heavy metals/metalloids on the relation to infants’ neurodevelopmental trajectories between 2 and 12 months. In paper 2, the association between Polybrominated Diphenyl Ether (PBDE), flame retardants, and functional connectivity of reading network was examined in a sample of 5-year-old children. Finally, paper 3 examines the relation between non-nutritive suck (NNS), which is an index of early brain development, and exposure to phthalates (compounds extensively used in home and care products). All three studies reveal significant associations between environmental exposure and subsequent child developmental delays and deficits using a variety of methods for measuring child development including neuroimaging, infant reflex behavior, and neurodevelopmental screening instruments. Collectively, these studies exemplify distinct empirical approaches for elucidating exposure-related effects on child development.

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