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Adoption is often a response to circumstances of severe adversity in the early years of life, with neglect, abuse and/or institutional care frequently involved. As a sort of natural experiment, adoption entails a radical change in developmental contexts and life circumstances. With considerable volume in recent years, adoption research is making significant contributions to answering some of the old questions in developmental psychology: what is the short- and long-term impact of negative experiences in the early years, what are the possibilities and limits of recovery over the life span, what are the circumstances that promote a more complete recovery. In addition to the implications for developmental science, adoption research makes a significant contribution to promote a better life for all those touched by adoption and to improvements in child welfare policies.