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Poster #5 - Adrenocortical and autonomic cross-system regulation in youth: A meta-analysis

Thu, March 23, 4:15 to 5:00pm, Salt Palace Convention Center, Floor: 1, Hall A-B

Abstract

Physiological stress response systems (SRS)–including the adrenocortical and autonomic (sympathetic and parasympathetic) systems–allow individuals to flexibly adapt to stressors and opportunities in their environments. Childhood and adolescence are particularly salient periods for the development of the SRS, setting the stage for subsequent health and adaptive functioning long-term. Although the development of the adrenocortical and autonomic systems are posited to function in highly coordinated ways, most studies remain limited to single system explorations. Burgeoning research is examining multi-system physiological regulation in the context of an acute stressor, yet the overall strength of these cross-system relations is difficult to ascertain due to variation in stress paradigms and sample characteristics. Thus, the current preregistered study uses meta-analysis to quantify the respective relations between adrenocortical, sympathetic, and parasympathetic functioning at rest and during reactivity in developmental samples between the ages 5-20 years. We will also examine moderators to determine if cross-system relations vary as a function of methodological characteristics (e.g., task type, time of day), age, or family socioeconomic status. Literature searches generated over 1000 articles and 146 met inclusion criteria post-screening. With data extraction currently underway, we will use multivariate mixed effects meta-regression via the metafor package in R (Viechtbauer, 2015) to generate our meta-analytic effect sizes of interest. Anticipated findings will advance our understanding of the development of multi-system physiological regulation, with theoretical and clinical implications that spur further research.

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