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As scientific collaboration and mobility benefit scientific careers of individual researches and scientific capacities of countries, changes over time-related to the productivity, research performance, and linkage capacities of researchers and countries can be detected. Authorship order provides critical information for the allocation of reward, and both collaboration and mobility enable researchers to expand the network of co-authors, institutions, and countries involved in the research. We hypothesize that both dimension of connectivity offer researchers the possibility to lead publications, as well as to expand the networks of co-authors and institutions with which they exchange knowledge. As bibliographic data embedded such important information about the changes in the position of authors in the byline of publications and the institutions involved in the research, we analyze these changes over time—using a disambiguated Web of Science dataset—to explore the extent to which collaboration and mobility relationships impact leadership the scientific workforce.