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The Trans-Pecos region of Texas is home to a diverse array of reptile and amphibian species occupying the various habitat associations found within the region. Surveys were conducted during the active season (March through November) to determine the relative abundance and habitat associations of reptile and amphibian species native to this region. Surveys were divided into two primary categories: road cruising and visual encounter surveys. Road cruising involved driving slowly on five standardized road routes repeatedly once per week at night and noting all specimens found. Visual encounter surveys involved hiking on five standardized trail routes repeatedly once per week and noting all specimens found. The most abundant reptile species found via road cruising surveys was Crotalus atrox, followed by Hypsiglena jani, Bogertophis subocularis, and Crotalus scutulatus. The most abundant reptile species found via visual encounter surveys was Sceloporus merriami, followed by Aspidoscelis scalaris, Sceloporus cowlesi, and Urosaurus ornatus. The most abundant amphibian species found via road cruising was Hyla arenicolor, followed by Scaphiopus couchii, Anaxyrus speciosus, and Anaxyrus punctatus. The most abundant amphibian species found via visual encounter surveys was Hyla arenicolor, followed by Anaxyrus punctatus, Lithobates berlandieri, and Scaphiopus couchii. All species were georeferenced and habitat associations for all species will be determined using a GIS. Determining the relative abundance and preferred habitat association of the diverse and often secretive herpetofauna of the Trans-Pecos allows for a better understanding of the conservation needs and priorities of this region.