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This study describes an intervention conducted with a 14 year-old girl with Down syndrome to foster communication in the classroom. Maria (pseudonym) withdrew from all communication with professionals and peers in the school environment following the divorce of her parents when she was ten years old, resulting in social isolation and academic disengagement. She did, however, communicate using speech at home with her parents and siblings. An intervention was designed using technology (music, PowerPoint, and self-directed home videos) focused on Maria’s interests and situated within an ethos of autonomy and dignity, with the goal of allowing Maria’s voice to emerge in the classroom. Findings based on observations and feedback from Maria, teachers and peers demonstrated increased communication and social engagement.