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The purpose of this meta-analysis is to examine the effects of computational thinking integration in STEM learning on students’ computational thinking in K-12 education. Following systematic procedures, we identified 19 qualified studies in which we extracted effect sizes on students’ computational in one-group pre-test to post-test designs. We also examined moderating variables, including student level, STEM content type, intervention duration, type of intervention (e.g., simulation), and computational thinking dimensions. Overall, we found a statistically significant large effect size (g = 0. 86 [95% CI of 0.498 to 1.227]; p < .001). The moderating variables were not statistically significant. We provide a discussion of the findings and present implications for future research and practice.