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Individual organizations acting alone cannot solve complex national and global challenges (e.g.: pandemic crises, climate change, etc.). Existing strategies and forms of collaboration do not span inter-functional silos and are predominantly designed to deal with static, localized instabilities. Decision-making in interconnected supply chains is relational, and dynamic and requires changed structures. It revolves around nonlinear networks involving multiple levels and different industries. This study investigates how businesses in these settings thrive by adapting relationship strategies and technological usage. It seeks to investigate trusted collaboration frameworks while considering transparency, data (sharing), benefit sharing (trust-and-gain sharing model), and legal or regulatory requirements.