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Cyberinfrastructure (CI) refers to a collection of distributed information, communication, and computer technologies (Atkins et al., 2003). Despite the trend toward integrated technologies, traditional technology adoption research often focuses on studying a single technology in isolation. The concept of cyberinfrastructure expands adoption research from looking at a single technology to consider multiple technologies by users. By taking a technologies-in-practice perspective and a combinatorial perspective, the author proposes seven predictors of cyberinfrastructure adoption and implementation.