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1-032 - Developmental Psychopathology and Neuroscience: Emotion Dysregulation at Multiple Levels of Analysis

Thu, April 6, 10:00 to 11:30am, Austin Convention Center, Meeting Room 17A

Session Type: Paper Symposium

Integrative Statement

This symposium will highlight the emerging scientific alliance between affective neuroscience and developmental psychopathology by focusing on emotion dysregulation. Emotion regulation is one of the most complex animal behaviors, and this ability takes a long time to develop and is highly subject to aberrant development and resulting psychopathologies. Relatedly, mature emotion regulation emerges from a complex interaction across genes, hormones, brain, context, and behavior. This symposium addresses this complexity by vertically integrating across multiple levels of bio-behavioral development, and it serves as a medium for presenting some of the most recent advances in Developmental Psychopathology and Neuroscience. To this end, four papers will be presented. Paper 1 focuses on the geneXenvironmental risk that influences stress-related brain systems involved in callous-unemotional traits in adolescents. Paper 2 will present functional magnetic resonance imaging (fMRI) and salivary cortisol associations to argue that early adverse experiences increase the risk for internalizing problems by altering hormonal and amygdala-prefrontal cortex development. Paper 3 will investigate depression in Mexican-American adolescents by examining the interrelationship between prefrontal function measured during an fMRI emotional faces task and parasympathetic nervous system activity. Finally, Paper 4 uses intervention to probe causal factors in the interactions between limbic-cortical connections and salivary cortisol as they relate to specific depression-related outcomes. Each presenter uses cutting-edge techniques to emphasize the power of assessing across multiple levels of analysis in an effort to elucidate the bio-behavioral mechanisms underlying the development of psychopathology.

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