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This talk maps how STS has engaged with “innovation” from the field’s beginnings to the present. My purpose is to insist that a critical stance toward innovation recognize its formative role in the very foundations of what STS is. At the same time, I hope to aid those who productively engage the contested idea of innovation as an analytical tool, object of inquiry, or normative posture. STS has a long-told origin story of an epistemological “high church” and an activist “low church.” In his influential essay “STS and an Engaged Program,” Sergio Sismondo revised this story by describing a growing hybrid of praxis-driven STS work. I describe how this praxis orientation has a longer history, how it relates to studies of innovation, and how it has long been fraught. I explore what role formal innovation studies (e.g. Gabriel Tarde or William Ogburn) played in the thought and organization of early STS units in Europe and the United States. I question how STS scholars from the 1970s onward approached innovation as a topic of critical inquiry--whether as a part of the military-industrial complex to be critiqued, a central feature of scientific discovery to understand, or as a normative goal of STS scholarship. I investigate the relationship between theories of innovation and constructivist theories of socio-technical change. I explore the political, financial, and personal entanglements of STS with pro-innovation institutions, projects, and ideologies. Finally, I ask how those who pursue this path today navigate such entanglements.